{"type":"standard","title":"FITM2","displaytitle":"FITM2","namespace":{"id":0,"text":""},"wikibase_item":"Q18049881","titles":{"canonical":"FITM2","normalized":"FITM2","display":"FITM2"},"pageid":43591769,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Ideogram_human_chromosome_20.svg/320px-Ideogram_human_chromosome_20.svg.png","width":320,"height":128},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Ideogram_human_chromosome_20.svg/474px-Ideogram_human_chromosome_20.svg.png","width":474,"height":189},"lang":"en","dir":"ltr","revision":"1081384485","tid":"3a50dbc1-b627-11ec-b484-c8913c1d602b","timestamp":"2022-04-07T04:00:14Z","description":"Protein-coding gene in the species Homo sapiens","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/FITM2","revisions":"https://en.wikipedia.org/wiki/FITM2?action=history","edit":"https://en.wikipedia.org/wiki/FITM2?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:FITM2"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/FITM2","revisions":"https://en.m.wikipedia.org/wiki/Special:History/FITM2","edit":"https://en.m.wikipedia.org/wiki/FITM2?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:FITM2"}},"extract":"Fat storage-inducing transmembrane protein 2 is a protein that in humans is encoded by the FITM2 gene. It plays a role in fat storage. Its location is 20q13.12 and it contains 2 exons. It is also a member of the FIT protein family that has been conserved throughout evolution. Conserved from Saccharomyces cerevisiae to humans is the capability to take fat and store it as cytoplasmic triglyceride droplets. While FIT proteins facilitate the segregation of triglycerides (TGs) into cytosolic lipid droplets, they are not involved in triglyceride biosynthesis. In mammals, both FIT2 and FIT1 from the same family are present, embedded in the wall of the endoplasmic reticulum (ER) where they regulate lipid droplet formation in the cytosol. In S. cerevisiae, it also plays a role in the metabolism of phospholipids. These TGs are in the cytoplasm, encapsulated by a phospholipid monolayer in configurations or organelles that have been given many different names including lipid particles, oil bodies, adiposomes, eicosasomes, and most prevalent in scientific research – lipid droplets.","extract_html":"
Fat storage-inducing transmembrane protein 2 is a protein that in humans is encoded by the FITM2 gene. It plays a role in fat storage. Its location is 20q13.12 and it contains 2 exons. It is also a member of the FIT protein family that has been conserved throughout evolution. Conserved from Saccharomyces cerevisiae to humans is the capability to take fat and store it as cytoplasmic triglyceride droplets. While FIT proteins facilitate the segregation of triglycerides (TGs) into cytosolic lipid droplets, they are not involved in triglyceride biosynthesis. In mammals, both FIT2 and FIT1 from the same family are present, embedded in the wall of the endoplasmic reticulum (ER) where they regulate lipid droplet formation in the cytosol. In S. cerevisiae, it also plays a role in the metabolism of phospholipids. These TGs are in the cytoplasm, encapsulated by a phospholipid monolayer in configurations or organelles that have been given many different names including lipid particles, oil bodies, adiposomes, eicosasomes, and most prevalent in scientific research – lipid droplets.
"}{"slip": { "id": 116, "advice": "One of the top five regrets people have is that they didn't stay in contact with friends."}}
{"slip": { "id": 167, "advice": "No one knows anyone else in the way you do."}}
{"type":"standard","title":"Front-engine, rear-wheel-drive layout","displaytitle":"Front-engine, rear-wheel-drive layout","namespace":{"id":0,"text":""},"wikibase_item":"Q4115030","titles":{"canonical":"Front-engine,_rear-wheel-drive_layout","normalized":"Front-engine, rear-wheel-drive layout","display":"Front-engine, rear-wheel-drive layout"},"pageid":816390,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/1/10/Automotive_diagrams_01_En.png/330px-Automotive_diagrams_01_En.png","width":320,"height":194},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/1/10/Automotive_diagrams_01_En.png","width":3067,"height":1863},"lang":"en","dir":"ltr","revision":"1272490912","tid":"9f6fc4f4-ddc4-11ef-b1c3-8fa367702d0d","timestamp":"2025-01-28T22:10:03Z","description":"Automobile layout","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Front-engine%2C_rear-wheel-drive_layout","revisions":"https://en.wikipedia.org/wiki/Front-engine%2C_rear-wheel-drive_layout?action=history","edit":"https://en.wikipedia.org/wiki/Front-engine%2C_rear-wheel-drive_layout?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Front-engine%2C_rear-wheel-drive_layout"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Front-engine%2C_rear-wheel-drive_layout","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Front-engine%2C_rear-wheel-drive_layout","edit":"https://en.m.wikipedia.org/wiki/Front-engine%2C_rear-wheel-drive_layout?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Front-engine%2C_rear-wheel-drive_layout"}},"extract":"A front-engine, rear-wheel-drive layout (FR), also called Système Panhard is a powertrain layout with an engine in front and rear-wheel-drive, connected via a drive shaft. This arrangement, with the engine straddling the front axle, was the traditional automobile layout for most of the pre-1950s automotive mechanical projects. It is also used in trucks, pickups, and high-floor buses and school buses.","extract_html":"
A front-engine, rear-wheel-drive layout (FR), also called Système Panhard is a powertrain layout with an engine in front and rear-wheel-drive, connected via a drive shaft. This arrangement, with the engine straddling the front axle, was the traditional automobile layout for most of the pre-1950s automotive mechanical projects. It is also used in trucks, pickups, and